News
Targeted mRNA Therapy for Osteoarthritis Using Disease‑Responsive Nanoparticles
1+ hour, 12+ min ago (489+ words) Targeted mRNA Therapy for Osteoarthritis Using Disease'Responsive Nanoparticles'Genetic Engineering and Biotechnology News Osteoarthritis (OA) affects more than 33 million adults in the United States and remains one of the most stubborn challenges in musculoskeletal medicine. The disease gradually erodes cartilage, causing…...
How Beige Fat Works to Promote Healthy Blood Pressure in Mice
1+ hour, 48+ min ago (529+ words) A mouse aorta with immunofluorescent tagging, emphasizing the close connection between vasculature and fat. [Weslie R. and William H. Janeway Laboratory of Molecular Metabolism at The Rockefeller University] The scientists found that in these animals, loss of beige fat increased blood vessel…...
Genetic Circuits Designed Using New AI/ML Technique
2+ hour, 29+ min ago (724+ words) Deciphering gene circuits can be tedious and immensely time consuming. Modifying, or designing gene circuits from previously identified pathways presents further challenges. "There are many possible designs for any given function, and finding the right one can be like looking…...
Cellares Inks Long-Term Lease for IDMO Smart Factory at Leiden Bio Science Park
6+ hour, 48+ min ago (180+ words) Co-founders Omar Kurdi (left) and Fabian Gerlinghaus (right) with The Cellares Cell Shuttle [Cellares] The leased premises comprise approximately 9,741 square meters (about 105,000 square feet) of laboratory and office space within the Nexus building in Leiden, a newly constructed life sciences…...
Improving Biopharma Sponsor Access to Clinical Trial Imaging Data
20+ hour, 41+ min ago (526+ words) Improving Biopharma Sponsor Access to Clinical Trial Imaging Data'Genetic Engineering and Biotechnology News Credit: imagestock / iStock / Getty Images Plus Yvete Toivola, PhD, is the vice president of Product Development at Flywheel, where she leads the development of imaging-centered data platforms…...
Simple Workflows for Complex Genomics: Expanding Clinically Relevant Findings with Enhanced Exomes
20+ hour, 57+ min ago (259+ words) In this GEN webinar, Guilherme Yamamoto, MD, PhD, and Sevana Yaghoubian will present a novel whole-exome assay for detecting high-confidence variants across multiple applications. The post Simple Workflows for Complex Genomics: Expanding Clinically Relevant Findings with Enhanced Exomes appeared first…...
Biologics Manufacturers Urged to Develop QC Plans Early
1+ day, 2+ hour ago (302+ words) By Vivienne Raper, PhD At a conference early next year, biologics manufacturers will be encouraged to develop a chemistry, manufacturing, and controls (CMC) management strategy for their reference material early in development to avoid later potential risks. "Agencies want you to…...
Regulatory Support Helping Biopharma to Embrace Platform Technologies
1+ day, 2+ hour ago (427+ words) By Gareth John Macdonald Credit: Gorodenkoff / iStock / Getty Images Plus Platform technologies'base systems used to make multiple products'are gaining in popularity in biopharma with more and more firms adopting modular manufacturing strategies to bring down costs. So says Vishnu Kumar,…...
Digital SHERLOCK: Rapid Detection and Resistance Profiling of Candida auris
1+ day, 3+ hour ago (623+ words) dSHERLOCK, a rapid CRISPR-based diagnostic that detects Candida auris from patient swabs and identifies antifungal resistance mutations, could enable faster treatment decisions and improved control of hospital outbreaks. The post Digital SHERLOCK: Rapid Detection and Resistance Profiling of Candida auris…...
Drugs from the Deep
1+ day, 7+ hour ago (358+ words) By Mike May, PhD From cancer treatments to antiviral therapies, some of today's most powerful medicines trace their origins to an unexpected place: the ocean. But while the sea holds enormous pharmaceutical promise, scientists say the challenge has always been…...